a stack is four questions at once: whether anything in it fights anything else, whether you are paying twice for the same mechanism, what it costs, and where to buy it. this is a safety tool, not medical advice, and not a recommendation to combine anything.
built and named by sean; open one for safety, overlap, cost and where to buy it
61 stacks shown
these verdicts are class-level heuristics; this is NOT medical advice in any capacity. this is purely for human harm reduction and informative purposes. no dosing NOR safety protocols can be enforced. liver-enzyme (CYP450) flags only fire on the serious, well-documented metabolic interactions; minor pharmacokinetic bumps are left unflagged, and no flag is not proof of safety. interactions will heavily depend on baseline neurology, dose, timing, and context. talk to a qualified professional before combining any drugs with one another, and inform yourself.
add up to six compounds; the checker reads every pair before you mix.
checking Codeine and Tramadol: at least one combination is flagged to avoid (1 to avoid). treat the red pairs as a reason to reconsider mixing.
two strong CNS depressants (opioid, benzodiazepine, z-drug, barbiturate, gabapentinoid, GABAergic or alcohol) add together on sedation and breathing; a leading cause of fatal respiratory depression.
one pair to avoidavoid
no outlet carries these
none of the outlets on the site carry these; the entries are reference only.
Codeine, Tramadol have no outlet here at all.
no listed prices
3 overlapssame lever, twice