spec sheet3 rows
Fosfogliv is a Russian two ingredient hepatoprotective capsule combining phosphatidylcholine with sodium glycyrrhizinate, the licorice-derived acid, marketed for chronic hepatitis and fatty liver.
- Marketed across Russia for chronic hepatitis and fatty liver
- One ingredient is genuinely active, unusual for a hepatoprotective
- Glycyrrhizinate calms inflammation in liver models
- Phosphatidylcholine carries the glycyrrhizin across for better absorption
- A licorice derived acid with real pharmacology behind it
Mechanism
Glycyrrhizic acid has anti-inflammatory and antifibrotic activity in liver models and is the component doing most of the work; phosphatidylcholine supplies membrane substrate and improves glycyrrhizin absorption. The same molecule inhibits 11-beta-hydroxysteroid dehydrogenase type 2, which lets act at the mineralocorticoid receptor, and that is why sustained licorice exposure produces pseudohyperaldosteronism with sodium retention, potassium loss and raised blood pressure. That risk carries straight over to this product and belongs in its safety section.
Safetyrisks and cautions, not medical advice
Fosfogliv is a fixed combination product in the blend class. A full adverse effect profile has not been compiled for this entry yet, so nothing here should be read as evidence that it is well tolerated; the absence is missing work rather than a finding. What is documented is what the compound is and what it is used for.
Subjective profileweighing the evidence above
Unusually for a hepatoprotective, one ingredient here is pharmacologically active in a way a person can feel; glycyrrhizinate inhibits 11-beta-hydroxysteroid dehydrogenase type 2, which allows cortisol to act at the mineralocorticoid receptor. That cuts both ways. It is why anti-inflammatory activity in liver models is plausible, and it is also why sustained use retains sodium, wastes potassium and raises blood pressure, a syndrome that has put people in hospital with weakness and arrhythmia from licorice alone. Anyone with hypertension, heart failure or a reason to be on a diuretic should stay away, and everyone else should treat long unbroken runs as the thing to avoid.
Where to buy
Suppliers
Vendors carrying Fosfogliv, with live product details and codes. Links are affiliate links that support the wiki at no cost to you.
RUPharma🌐
Fosfogliv