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for educational and safety purposes
Arimidex and Exemestane both come up in the same conversations. Arimidex: Arimidex is a brand name for anastrozole, a nonsteroidal aromatase inhibitor used mainly to treat hormone-receptor-positive breast cancer in postmenopausal women. Exemestane: Exemestane is a steroidal aromatase inhibitor used chiefly to treat hormone-receptor-positive breast cancer in postmenopausal women.
Arimidex is a brand name for anastrozole, a nonsteroidal aromatase inhibitor used mainly to treat hormone-receptor-positive breast cancer in postmenopausal women. By blocking the aromatase enzyme it sharply lowers the body's estrogen, slowing cancers that depend on estrogen to grow, and it is used as adjuvant therapy after surgery, for advanced disease, and, as shown in the IBIS-II trial, for prevention in high-risk women. Its common side effects, including joint pain, hot flashes, and bone thinning, are direct consequences of that profound estrogen suppression, which is also the basis of concern about effects on cognition.
Exemestane is a steroidal aromatase inhibitor used chiefly to treat hormone-receptor-positive breast cancer in postmenopausal women. Sold under the brand name Aromasin, it lowers the body's estrogen supply by permanently inactivating aromatase, the enzyme that builds estrogen, and is taken as a once-daily oral tablet. It is also used off-label, mainly by men, to keep estrogen levels in check.
both fingerprints on one instrument; where the marks line up the two compounds work the same lever, where a slot goes dark only one of them touches it. read straight from each entry's affinity table; nothing here is invented.
non-steroidal inhibitor
reduces
blocks
blocks
inhibits
blocks
modulates
activates
strengths are the entries' qualitative ratings (strong / moderate / weak); Ki and EC50 figures appear where an entry records them.