Exomitin is a topical hydrogel carrying the mitochondria-targeted antioxidant SkQ1, applied to irritated, burned or damaged skin.
- Topical hydrogel carrying the SkQ1 mitochondrial antioxidant
- Applied to irritated, burned or damaged skin
- Membrane potential concentrates it hundreds of times inside mitochondria
- Recycled by the respiratory chain, so a little lasts
- One of the cleverest molecules in the catalogue
Mechanism
SkQ1 is a plastoquinone head group tethered to a triphenylphosphonium cation, and the positive charge is what makes it accumulate hundreds of times over inside mitochondria, driven by the inner membrane potential. Once there the quinone intercepts lipid peroxyl radicals in the inner membrane and is recycled back to its reduced form by the respiratory chain, so a small amount keeps working rather than being consumed.
Safetyrisks and cautions, not medical advice
Exomitin is a single molecule in the topical formula class. A full adverse effect profile has not been compiled for this entry yet, so nothing here should be read as evidence that it is well tolerated; the absence is missing work rather than a finding. What is documented is what the compound is and what it is used for.
Subjective profileweighing the evidence above
Exomitin carries one of the cleverest molecules in this catalogue and attaches it to one of the softest indications. Tethering a plastoquinone to a lipophilic cation so the mitochondrial membrane potential concentrates it hundreds of times over inside the organelle is elegant design, and recycling by the respiratory chain means a small quantity keeps working rather than being used up. What has never been shown is that any of that matters to a burn or an irritated patch of skin, where the limiting problems are barrier repair and infection rather than mitochondrial lipid peroxidation. Curiosity value high, expected result low.
Where to buy
Suppliers
Vendors carrying Exomitin, with live product details and codes. Links are affiliate links that support the wiki at no cost to you.
RUPharma🌐
Exomitin