data + articles · 2 listed
newest 2018spec sheet10 rows
3-FPM is a fluorinated analog of phenmetrazine, an older appetite-suppressant stimulant built on a morpholine ring rather than a simple amphetamine backbone. It releases dopamine and norepinephrine, giving a clear-headed, functional stimulation that people often compare to a gentler amphetamine. It still carries real cardiovascular and dependence risks.
- Clear-headed stimulation
- Improved focus
- Appetite suppression
- Raised heart rate and blood pressure
- Vasoconstriction
- Insomnia
Mechanism
3-FPM is a - releasing agent, meaning it drives release of norepinephrine and dopamine into the via their transporters, with norepinephrine effects generally leading. The morpholine ring of the phenmetrazine skeleton distinguishes it structurally from classic amphetamines, but the functional stimulant effect is similar. It has little meaningful activity.
receptor fingerprint
transporter (NET)Releaser
()Releaser
Dosingtypical ranges, not medical advice
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Safetyrisks and cautions, not medical advice
It raises heart rate and blood pressure and can cause a pounding heart, chest discomfort, and vasoconstriction, especially when redosed. The relatively long, clear-headed effect makes compulsive redosing and severe sleep loss easy, and stacking with other stimulants or MAOIs adds serious cardiovascular and hypertensive risk. Heavy use can bring anxiety and dependence. Not medical advice.
Subjective profileweighing the evidence above
The clear-headed, long-running character is precisely what makes compulsive redosing easy, and there are two citations behind the whole compound. Not something to run regularly, and never stacked with other stimulants or an MAOI.
Resources
This entry is here for reference.
Research
- 1.Fluorinated phenmetrazine "legal highs" act as substrates for high-affinity monoamine transporters of the SLC6 family.
- 2.Adverse events related to the new psychoactive substance 3-fluorophenmetrazine - results from the Swedish STRIDA project.
2 listed here; entry last updated July 2026
Reviews
My notesprivate to this device
FAQ
Is 3-FPM an amphetamine?
Not exactly; it is a phenmetrazine analog with a morpholine ring, though it produces a similar releasing-agent stimulant effect.
Why is redosing a concern?
Its long, clear-headed character makes it easy to keep topping up, which drives sleep loss and cardiovascular strain.
Does it mix safely with other stimulants?
No. Combining stimulants stacks cardiovascular risk, and MAOIs are especially dangerous.
Adverse effects
- Raised heart rate and blood pressure
- Vasoconstriction
- Insomnia
Notes and cautions
- Compulsive redosing