spec sheet10 rows
3-FA is amphetamine with a fluorine at the meta (3) position of the ring. It releases dopamine and norepinephrine much like amphetamine, with a modest serotonin component, giving a fairly straightforward stimulant character. It carries the standard cardiovascular and dependence risks of the amphetamine family.
- Stimulation and energy
- Elevated mood
- Wakefulness
- Raised heart rate and blood pressure
- Overheating risk
- Appetite loss
Mechanism
3-FA is a substituted amphetamine that acts mainly as a releasing agent at the and transporters, raising levels of both; it also has some -releasing activity, generally less pronounced than its para-substituted cousin 4-FA. The net effect is a stimulating, euphoric profile weighted toward dopamine and norepinephrine.
receptor fingerprint
transporter (NET)Releaser
()Releaser
transporter (SERT)Releaser
Safetyrisks and cautions, not medical advice
As a monoamine releaser it raises heart rate and blood pressure and can cause overheating, especially in warm or high-activity settings. Its serotonin activity means combining it with MAOIs or other serotonergic drugs can risk serotonin toxicity, and stacking with other stimulants adds cardiac strain. Redosing, sleep loss, and a harsh comedown are common. Not medical advice.
Subjective profileweighing the evidence above
Nothing here that amphetamine does not do better and under supervision. Two citations, real overheating and blood pressure risk, and a clear path to dependence make this a research chemical to leave alone.
Resources
This entry is here for reference.
Research
- 1.Locomotor and discriminative stimulus effects of fluorinated analogs of amphetamine and methamphetamine in mice and rats.
- 2.Relationship between the serotonergic activity and reinforcing effects of a series of amphetamine analogs.
2 listed here; entry last updated August 2026
Reviews
My notesprivate to this device
FAQ
Is 3-FA more like a stimulant or an entactogen?
It leans stimulant, with less of the empathogenic warmth than 4-FA because its serotonin activity is weaker.
Does it interact with antidepressants?
Yes. Its serotonin release makes MAOIs and other serotonergic drugs a real serotonin-toxicity risk.
How long does it last?
Effects typically run several hours, and redosing can stretch a session into a long, sleep-disrupting run.
Adverse effects
- Raised heart rate and blood pressure
- Overheating risk
- Appetite loss
Notes and cautions
- Comedown