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for educational and safety purposes
AL-LAD and ETH-LAD both come up in the same conversations; they overlap on Serotonin. AL-LAD: AL-LAD (6-allyl-6-nor-LSD) is a lysergamide psychedelic closely related to LSD, differing by replacement of the N6 methyl group with an allyl group. ETH-LAD: ETH-LAD (6-ethyl-6-nor-lysergic acid diethylamide) is a lysergamide psychedelic and close structural analogue of LSD in which the N-6 methyl group of the ergoline scaffold is replaced by an ethyl group.
AL-LAD (6-allyl-6-nor-LSD) is a lysergamide psychedelic closely related to LSD, differing by replacement of the N6 methyl group with an allyl group. Like other serotonergic hallucinogens it acts primarily through agonism at the 5-HT2A receptor, and in the mouse head-twitch response assay it produces the characteristic inverted U-shaped dose-response curve, proving only slightly less potent than LSD itself. Users describe strongly visual, colorful effects with a duration comparable to LSD but often somewhat shorter and milder in strength and comedown. Analytical and metabolic studies have detailed its structure, biotransformation, and its acylated prodrug forms such as 1P-AL-LAD and 1cP-AL-LAD, which are hydrolyzed to AL-LAD in the body. A published case of fatal ventricular dysrhythmia associated with its use indicates that, despite its reputation as a gentler LSD analogue, it is not without cardiovascular risk.
ETH-LAD (6-ethyl-6-nor-lysergic acid diethylamide) is a lysergamide psychedelic and close structural analogue of LSD in which the N-6 methyl group of the ergoline scaffold is replaced by an ethyl group. Like LSD and other serotonergic hallucinogens it acts as an agonist at the 5-HT2A receptor, the principal molecular target mediating classical psychedelic effects, and lysergamides in this series reliably induce the 5-HT2A-dependent head-twitch response in rodents. It emerged as a research chemical distributed on blotters and in powders, alongside its 1-acyl prodrug 1P-ETH-LAD, which hydrolyses to ETH-LAD in serum. Users and comparative surveys describe effects broadly similar in time course to LSD but often report greater potency, more pronounced visual activity, and a heavier or more anxiogenic body load, and its analytical and metabolic profiles have been characterised to support forensic detection.
both fingerprints on one instrument; where the marks line up the two compounds work the same lever, where a slot goes dark only one of them touches it. read straight from each entry's affinity table; nothing here is invented.
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strengths are the entries' qualitative ratings (strong / moderate / weak); Ki and EC50 figures appear where an entry records them.