sodium/water excretion

Every compound in the sci-wiki that affects sodium/water excretion; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

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Lisinopril + Hydrochlorothiazide

Lisinopril + hydrochlorothiazide is a fixed-dose combination medication that pairs an ACE inhibitor with a thiazide diuretic in a single tablet to treat high blood pressure. Lisinopril relaxes blood vessels by blocking the angiotensin-converting enzyme, while hydrochlorothiazide helps the kidneys remove excess salt and water. Combining the two lowers blood pressure more than either alone and is typically used when a single drug is not enough. It is sold under brand names such as Zestoretic and Prinzide.

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Telmisartan + Cilnidipine + Chlorthalidone

Telmisartan with cilnidipine and chlorthalidone is a fixed-dose combination medicine that unites three blood-pressure-lowering drugs with complementary actions in a single tablet. It pairs an angiotensin II receptor blocker (telmisartan), a dual L-type and N-type calcium channel blocker (cilnidipine), and a thiazide-like diuretic (chlorthalidone). Single-pill combinations of this kind are used when hypertension is not adequately controlled by one or two agents, and they aim to simplify treatment and improve adherence.

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Diuretic

Torsemide

Torsemide, also spelled torasemide, is a loop diuretic used to treat fluid overload and swelling associated with heart failure, kidney disease, and liver disease, as well as high blood pressure [1]. It increases urine output by blocking salt reabsorption in the kidney, and compared with the older loop diuretic furosemide it is more completely absorbed and longer acting [1]. Marketed under names such as Demadex, it appears on the World Health Organization's List of Essential Medicines.

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