menopausal symptoms

Every compound in the sci-wiki that affects menopausal symptoms; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

3 sourced · 0 reference

←menopausal symptoms3/3

Hormone

Conjugated Estrogens

Conjugated estrogens, best known by the brand name Premarin, are a medication made from a mixture of estrogen hormones extracted from the urine of pregnant mares [1][2]. They are used mainly as menopausal hormone therapy, to relieve hot flashes and vaginal dryness and to help prevent osteoporosis, and also to treat other conditions of low estrogen [1][2]. Introduced in the 1940s, they act on estrogen receptors throughout the body; landmark trials later clarified that, like other hormone therapies, they carry risks including blood clots, stroke and, in combination with a progestogen, breast cancer [1][3].

1 outlet

Hormone

Estradiol

Estradiol, often abbreviated E2, is a steroid hormone and the most potent of the naturally occurring estrogens, the principal group of female sex hormones. Produced chiefly by the ovaries, it governs the development of female secondary sexual characteristics and the menstrual cycle, and it also plays important roles in bone, brain, and cardiovascular health in both sexes. As a medicine it is used in menopausal hormone therapy, hormonal contraception, feminizing hormone therapy for transgender women, and the treatment of certain hormone deficiencies. It is available in many forms, including tablets, patches, gels, and injections.

2 outlets

Hormone

Estradiol Valerate

Estradiol valerate is an estrogen medication and an ester prodrug of estradiol, the main natural estrogen. Once in the body it is split by enzymes into estradiol and valeric acid, so its effects are essentially those of estradiol itself. It is used in menopausal hormone therapy, as part of some hormonal contraceptives, in feminizing hormone therapy for transgender women, and, historically, in the palliative treatment of prostate cancer. It is taken by mouth as a tablet or given as a long-acting oil injection into muscle.

1 outlet