melanocytes

Every compound in the sci-wiki that affects melanocytes; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

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Dermatological

Azelaic Acid

Azelaic acid is a naturally occurring saturated dicarboxylic acid (chemically nonanedioic acid, a nine-carbon molecule) used mainly as a topical treatment in dermatology. It is found in cereal grains such as wheat, rye, and barley and is produced on the skin by Malassezia yeast. Applied to the skin it treats acne, rosacea, and pigmentation problems such as melasma, working through antibacterial, pore-normalizing, anti-inflammatory, and pigment-reducing actions.

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Blend

Hydroquinone + Tretinoin + Fluocinolone Acetonide

Hydroquinone + Tretinoin + Fluocinolone Acetonide is a triple-combination topical cream used to treat melasma, a chronic facial hyperpigmentation. It brings together a depigmenting agent (hydroquinone), a retinoid (tretinoin) and a low-potency corticosteroid (fluocinolone acetonide) in a single formulation. Marketed in the United States as Tri-Luma and rooted in the older Kligman formula, it is widely regarded as one of the most effective topical treatments for melasma.

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Blend

Hydroquinone + Tretinoin + Mometasone

Hydroquinone + Tretinoin + Mometasone is a triple-combination topical cream used to lighten melasma and other facial hyperpigmentation. It is a modified version of the classic Kligman formula, pairing the depigmenting agent hydroquinone and the retinoid tretinoin with mometasone, a stronger corticosteroid than the fluocinolone used in the original. The formulation is widely prescribed and sold in some regions, though the more potent steroid raises particular safety concerns.

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