kidney

Every compound in the sci-wiki that affects kidney; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

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Nootropic

Losartan

Losartan is an angiotensin II receptor blocker (ARB) used mainly to treat high blood pressure and to protect the kidneys in people with type 2 diabetes. It was the first drug of its class to reach the market, working by blocking the angiotensin II type 1 (AT1) receptor so that blood vessels relax and the heart and kidneys face less strain. Taken by mouth as the potassium salt, it is now a widely available, low-cost generic on the World Health Organization list of essential medicines.

2 outlets

Cardiovascular

Spironolactone

Spironolactone is a medication that blocks the hormone aldosterone at the mineralocorticoid receptor, making it a potassium-sparing diuretic and antimineralocorticoid. It is used to treat heart failure, resistant high blood pressure, fluid retention, and primary hyperaldosteronism, and because it also weakly blocks androgen receptors it is widely prescribed for acne, hirsutism, and as part of feminizing hormone therapy. Discovered in the late 1950s, it is a generic drug on the World Health Organization's list of essential medicines.

2 outlets

Diuretic

Torsemide

Torsemide, also spelled torasemide, is a loop diuretic used to treat fluid overload and swelling associated with heart failure, kidney disease, and liver disease, as well as high blood pressure [1]. It increases urine output by blocking salt reabsorption in the kidney, and compared with the older loop diuretic furosemide it is more completely absorbed and longer acting [1]. Marketed under names such as Demadex, it appears on the World Health Organization's List of Essential Medicines.

2 outlets