for educational and safety purposes
Every compound in the sci-wiki that affects bacterial infection; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.
7 sourced · 0 reference
Azithromycin is a broad-spectrum antibiotic in the macrolide family, specifically the first of the azalide subclass, sold under brand names such as Zithromax and the Z-Pak. It treats a range of bacterial infections, including respiratory, skin, and sexually transmitted infections. Discovered by scientists at the Croatian company Pliva in the early 1980s, it is known for concentrating heavily in body tissues and having a long half-life, which allows short, simple courses of treatment.
Bacitracin zinc, neomycin, and polymyxin B is a topical antibiotic combination, sold over the counter as triple antibiotic ointment under brand names such as Neosporin. Blended into a petroleum-jelly base, the three antibiotics attack bacteria in complementary ways and together cover a wide range of gram-positive and gram-negative organisms. It is applied to minor cuts, scrapes, and burns to lower the chance of skin infection while a wound heals.
Cefixime is an orally administered third-generation cephalosporin antibiotic used to treat a range of bacterial infections [1][2]. It works by disrupting construction of the bacterial cell wall and is notably resistant to breakdown by many bacterial beta-lactamase enzymes [2]. Common uses include urinary tract infections, middle-ear infections, pharyngitis, and certain respiratory and sexually transmitted infections [2][3]. First patented in 1979 and approved in the United States in 1989, cefixime is listed on the World Health Organization Model List of Essential Medicines [1].
Cephalexin, also spelled cefalexin, is a first-generation cephalosporin antibiotic taken by mouth to treat a variety of common bacterial infections [1][2]. It works by blocking construction of the bacterial cell wall and is used chiefly against gram-positive organisms, in conditions such as skin infections, strep throat, ear infections, and urinary tract infections [1][2]. First marketed in 1969 under the brand name Keflex, it is inexpensive, widely available as a generic, and listed on the World Health Organization Model List of Essential Medicines [1]. It is generally well tolerated, with digestive upset among the more common side effects [1][2].
Ciprofloxacin is a broad-spectrum fluoroquinolone antibiotic used to treat a range of bacterial infections, including urinary, respiratory, gastrointestinal, bone, and skin infections. It works by blocking bacterial enzymes needed to copy and repair DNA and is especially active against Gram-negative bacteria. First introduced by Bayer in the late 1980s, it appears on the World Health Organization list of essential medicines but now carries strong safety warnings and faces rising bacterial resistance.
Clarithromycin is a macrolide antibiotic, a semisynthetic derivative of erythromycin developed to be more acid-stable and better absorbed. It is used to treat respiratory tract infections, skin and soft-tissue infections, Helicobacter pylori, and certain mycobacterial infections. It stops bacteria from making proteins, and it is notable both for interacting with many other medicines and for cautions about heart rhythm.
Ofloxacin is a broad-spectrum antibiotic of the fluoroquinolone class, active against a wide range of gram-positive and gram-negative bacteria. It is a racemic mixture, and its biologically active half is the compound now marketed separately as levofloxacin. Introduced in the 1980s, it is used for respiratory, urinary, skin, and certain sexually transmitted infections, and as eye and ear drops for local infections. Like other fluoroquinolones it can cause uncommon but serious effects such as tendon injury, and its role has narrowed as bacterial resistance has spread.