LAE-32

LAE-32, or lysergic acid monoethylamide, is a lysergamide closely related to LSD in which one of the two ethyl groups of the diethylamide is removed, leaving a single ethylamide. It retains activity at serotonin receptors and is psychoactive, but historical human and animal studies from the 1950s reported it to be substantially less potent than LSD and more sedating or dreamy in character rather than strongly hallucinogenic. The same monoethylamide also appears as a minor metabolite of LSD, detectable at trace levels in plasma after controlled LSD administration. Owing to its early characterization and limited use, the modern literature on LAE-32 is sparse and consists largely of these mid-twentieth-century comparisons with LSD.