for educational and safety purposes
Every compound in the sci-wiki that affects vascular endothelium; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.
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Hesperidin is a flavanone glycoside (a plant flavonoid bound to a sugar) that is abundant in citrus fruit, especially the peel and white pith of oranges and lemons; its sugar-free form is called hesperetin. It is best understood as a venous and vascular supplement; it is best known as a partner to diosmin for chronic venous insufficiency (poor return of blood from the legs) and hemorrhoids, with lighter support for antioxidant, anti-inflammatory, and modest metabolic effects on blood sugar and lipids.
Vesugen is a synthetic tripeptide composed of lysine, glutamic acid and aspartic acid (Lys-Glu-Asp). It is one of the short peptide bioregulators developed in Russia and is described as a vascular peptide, meaning it is intended to support the blood vessels and their inner lining, especially in aging. Research on it comes mainly from Russian laboratories, and it is not an approved medicine in Western countries.