melanin synthesis

Every compound in the sci-wiki that affects melanin synthesis; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

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Glutathione + Kojic Acid

Glutathione and kojic acid is a combination of two agents used together in cosmetic skin-lightening and brightening products. Glutathione is a naturally occurring antioxidant tripeptide that can shift melanin production toward lighter pigments, while kojic acid is a fungal-derived compound that inhibits tyrosinase, the key enzyme in melanin synthesis. Marketed in creams, soaps, and oral supplements, the pairing is intended to reduce hyperpigmentation and even out skin tone, although the strength of the clinical evidence varies.

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Hydroquinone + Tretinoin + Mometasone

Hydroquinone + Tretinoin + Mometasone is a triple-combination topical cream used to lighten melasma and other facial hyperpigmentation. It is a modified version of the classic Kligman formula, pairing the depigmenting agent hydroquinone and the retinoid tretinoin with mometasone, a stronger corticosteroid than the fluocinolone used in the original. The formulation is widely prescribed and sold in some regions, though the more potent steroid raises particular safety concerns.

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