heart: nootropics and compounds | sci-wiki

Adrenaline (Epinephrine)

Adrenaline, also called epinephrine, is a hormone and neurotransmitter of the catecholamine class that the body releases mainly from the adrenal glands in response to stress. It drives the fight-or-flight response, quickening the heartbeat, opening the airways, and redirecting blood to the muscles to ready the body for exertion. As a medication it is the first-line treatment for the severe allergic reaction anaphylaxis and is also used in cardiac arrest and other emergencies, and it appears on the World Health Organization's List of Essential Medicines.

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ARB

Candesartan

Candesartan is an angiotensin II receptor blocker (ARB), a class of drugs that lower blood pressure by blocking the effects of the hormone angiotensin II. Marketed mainly as Atacand and taken by mouth as the prodrug candesartan cilexetil, it is used to treat high blood pressure and chronic heart failure. It has also been studied for preventing migraine and, like other ARBs, is generally well tolerated.

1 outlet

Beta-Blocker

Carvedilol

Carvedilol is a medication of the beta-blocker class that also blocks alpha-1 adrenergic receptors, sometimes described as a third-generation beta-blocker. Sold under brand names such as Coreg, it is used chiefly to treat chronic heart failure, high blood pressure, and left ventricular dysfunction after a heart attack. By blunting the effects of adrenaline on the heart and relaxing blood vessels, and through additional antioxidant properties, it improves survival in heart failure and is considered a standard therapy.

1 outlet

Cardiovascular

Cilnidipine

Cilnidipine is a dihydropyridine calcium channel blocker used to treat high blood pressure. Unlike most drugs in its class, it blocks both L-type and N-type calcium channels, the latter located on sympathetic nerve endings, which lets it lower blood pressure while limiting the reflex rise in heart rate seen with some other calcium antagonists. It was approved for medical use in the mid-1990s and is marketed mainly in Japan and several other Asian countries.

1 outlet

Cardiovascular

Enalapril

Enalapril is an angiotensin-converting enzyme (ACE) inhibitor used to treat high blood pressure and chronic heart failure and to help protect kidney function in some patients. It is a prodrug that the body converts into its active form, enalaprilat, which relaxes blood vessels and reduces the strain on the heart. Landmark trials established that it prolongs survival in people with heart failure, and it is taken as an oral tablet.

1 outlet

Mitochondrial

Urolithin B

Urolithin B is one of the urolithins, compounds produced by gut bacteria from the ellagitannins and ellagic acid in foods such as pomegranates, walnuts and berries. Chemically it is a monohydroxy dibenzopyranone and a downstream product of the same microbial pathway that yields urolithin A. It has been studied mainly for effects on skeletal muscle, where laboratory and animal work suggests it can promote muscle growth [1][2].

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