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Every compound in the sci-wiki that affects fibroblasts; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.
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Human placenta extract is a preparation derived from human placental tissue, typically processed into a hydrolysate that concentrates amino acids, peptides, growth factors, and other bioactive molecules. It has been used mainly in parts of East Asia, particularly Korea and Japan, where injectable forms are prescribed for indications such as menopausal symptoms, fatigue, and liver complaints. Its use elsewhere is limited, and much of the clinical research is small in scale.
Pirfenidone is an orally administered antifibrotic and anti-inflammatory drug used to treat idiopathic pulmonary fibrosis, a progressive scarring disease of the lungs. Chemically it is a small pyridinone molecule (5-methyl-1-phenylpyridin-2-one) that slows the loss of lung function by dampening the growth factors and collagen production that drive fibrosis. First approved in Japan in 2008 and later cleared across Europe, North America and elsewhere, it is sold under brand names such as Esbriet and Pirespa.