factor Xa

Every compound in the sci-wiki that affects factor xa; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

3 sourced · 0 reference

←factor xa3/3

Anticoagulant

Apixaban

Apixaban is a direct oral anticoagulant, sold under the brand name Eliquis, that works by directly blocking clotting factor Xa. Developed by Bristol-Myers Squibb and Pfizer and approved in the early 2010s, it is used to prevent strokes in people with atrial fibrillation and to treat and prevent deep vein thrombosis and pulmonary embolism. Compared with the older drug warfarin, it does not require routine blood monitoring and carries a lower risk of bleeding into the brain.

1 outlet

Anticoagulant

Enoxaparin

Enoxaparin is a low-molecular-weight heparin, an injectable anticoagulant or blood thinner used to prevent and treat blood clots. It is produced by breaking standard heparin into shorter fragments, which gives it a more predictable effect that usually needs no routine blood-test monitoring. It is used in conditions such as deep-vein thrombosis, pulmonary embolism, and acute coronary syndromes, and is sold under the brand name Lovenox.

1 outlet

Anticoagulant

Rivaroxaban

Rivaroxaban is an oral anticoagulant, or blood thinner, that works by directly inhibiting factor Xa, a key enzyme in the clotting cascade. It was the first orally active direct factor Xa inhibitor to be marketed and is used to prevent and treat blood clots. Developed by Bayer, it is sold mainly under the brand name Xarelto.

2 outlets