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Every compound in the sci-wiki that affects colon health; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.
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Butyric acid (butanoic acid) is a short-chain fatty acid with the formula CH3CH2CH2COOH, present in the body mainly as its salt, butyrate. It is produced when gut bacteria ferment dietary fiber in the colon, and it also occurs naturally in butter and other dairy fats. Butyrate serves as the primary energy source for the cells lining the colon and is widely studied for its roles in gut and metabolic health.
Tributyrin, also called glyceryl tributyrate, is a triglyceride made of glycerol esterified with three molecules of butyric acid, and it occurs naturally in butter. It serves as a stable, orally absorbed prodrug that releases butyrate into the body, letting the short-chain fatty acid reach the bloodstream more effectively than butyrate salts [1]. Because butyrate acts as a histone deacetylase inhibitor, tributyrin has been studied in cancer, gut health and, more recently, as a postbiotic dietary supplement [4].