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Every compound in the sci-wiki that affects colon; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.
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Lactulose is a synthetic disaccharide made of the sugars galactose and fructose that the human small intestine cannot absorb. It works as an osmotic laxative and is used to relieve chronic constipation and to treat hepatic encephalopathy, the confusion that arises when a failing liver allows ammonia to build up. Because gut bacteria ferment it, lactulose also acts as a prebiotic, and it appears on the World Health Organization's list of essential medicines.
Mesalamine, also known as mesalazine or 5-aminosalicylic acid (5-ASA), is an anti-inflammatory medication of the aminosalicylate class used to treat inflammatory bowel disease. Chemically related to salicylic acid, it works locally on the lining of the intestine to reduce inflammation and is a mainstay of treatment for ulcerative colitis, where it is used both to bring on and to maintain remission. It is delivered in oral tablets and capsules designed to release the drug in the colon, as well as in rectal suppositories and enemas.