cardiovascular risk

Every compound in the sci-wiki that affects cardiovascular risk; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

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Blend

Aspirin + Atorvastatin

Aspirin + Atorvastatin is a fixed-dose combination medicine that pairs low-dose aspirin, an antiplatelet drug, with atorvastatin, a cholesterol-lowering statin. It is used mainly to prevent cardiovascular events such as heart attacks and strokes in people who already have, or are at high risk of, cardiovascular disease. Combining the two drugs in a single pill is intended to simplify treatment and improve adherence, and such fixed-dose combinations underpin the wider polypill approach to cardiovascular prevention.

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Statin

Atorvastatin

Atorvastatin is a lipid-lowering medication in the statin class, sold originally under the brand name Lipitor. It works by inhibiting HMG-CoA reductase, a liver enzyme central to cholesterol production, which lowers LDL (low-density lipoprotein) cholesterol and reduces the risk of heart attacks and strokes. Introduced in 1996 and once the best-selling drug in the world, it is now a widely used inexpensive generic and appears on the World Health Organization's List of Essential Medicines.

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Supplement

Icosapent Ethyl

Icosapent ethyl is a prescription omega-3 medication, the ethyl ester of eicosapentaenoic acid (EPA), a fatty acid found in fish oil. Unlike ordinary fish-oil supplements it is a highly purified form containing only EPA and no DHA. Sold under the brand Vascepa, it is used to lower very high triglycerides and, in people already on statins, to reduce the risk of cardiovascular events.

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