for educational and safety purposes
Every compound in the sci-wiki that affects bladder neck; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.
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Alfuzosin is an alpha-1 adrenergic receptor antagonist, a type of alpha blocker used to relieve the urinary symptoms of an enlarged prostate. Sold under brand names such as Uroxatral and Xatral, it relaxes smooth muscle in the prostate and bladder neck to improve urine flow without shrinking the prostate itself. Taken as a once-daily extended-release tablet, it is a common first-line medical treatment for benign prostatic hyperplasia.
Silodosin is a selective alpha-1A adrenergic receptor antagonist, a type of alpha blocker, used to relieve the urinary symptoms of benign prostatic hyperplasia (BPH). By relaxing smooth muscle in the prostate, bladder neck, and urethra, it improves urine flow in men with an enlarged prostate. First approved in Japan in 2006 and sold under brand names such as Rapaflo and Urorec, it is noted for a high selectivity that limits blood-pressure effects but commonly causes abnormal ejaculation.
Tamsulosin is a medication of the alpha-1 adrenergic receptor antagonist class, commonly called an alpha blocker, sold under brand names such as Flomax. It is used mainly to ease the urinary symptoms of an enlarged prostate and to help small stones pass through the ureter. It works by relaxing smooth muscle in the prostate, bladder neck, and urinary tract rather than by shrinking the prostate.