class, effects, and the receptor fingerprint, side by side; add up to four, then source the whole stack
Popular head-to-heads →HGF / c-Metproposed positive modulator
PI3K/Akt, MAPK/ERKactivates
Hepatocyte growth factor (HGF), the ligandDirect binding; source retracted
MET / c-Met receptor tyrosine kinase (HGF receptor)Proposed positive allosteric modulator; reported to promote c-Met phosphorylation only in the presence of sub-threshold HGF, not as a standalone agonist
PI3K/AKT signalling (downstream)Pathway activation; effects reversed by the PI3K inhibitor wortmannin
AT4 receptor / insulin-regulated aminopeptidase (IRAP)Inherited from the parent angiotensin IV pharmacology; proposed but never demonstrated for Dihexa specifically
BDNF / TrkBupregulates
MC4R (melanocortin)agonist
Prolyl endopeptidaseinhibits
Dopamine / Serotoninraises turnover
checking Dihexa and Semax: no adverse interactions were flagged (1 compatible pair); the pairs read as compatible at the class level.
carries no adverse class-level interaction with most compounds.
General educational info, not medical advice.
The vendors that carry the most of your 2 picks; fewer vendors, fewer codes, less shipping.