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for educational and safety purposes
Heroin and Morphine both come up in the same conversations; they overlap on Mu-opioid receptor and Pain. Heroin: Heroin (diacetylmorphine, or diamorphine in medicine) is a fast-acting semisynthetic opioid made by acetylating morphine. Morphine: Morphine is a potent opioid analgesic and the principal alkaloid of opium, the dried latex of the opium poppy (Papaver somniferum).
Heroin (diacetylmorphine, or diamorphine in medicine) is a fast-acting semisynthetic opioid made by acetylating morphine. It is a prodrug; the body strips the acetyl groups off to release 6-monoacetylmorphine and morphine, which switch on mu-opioid receptors to produce pain relief, a rush of euphoria, and dangerous slowing of breathing.
Morphine is a potent opioid analgesic and the principal alkaloid of opium, the dried latex of the opium poppy (Papaver somniferum). It relieves moderate to severe pain by activating opioid receptors in the brain and spinal cord, and it has been a mainstay of pain medicine since it was first isolated in the early nineteenth century. A controlled substance on the World Health Organization's list of essential medicines, morphine is highly effective but carries substantial risks of dependence, addiction and potentially fatal respiratory depression.
both fingerprints on one instrument; where the marks line up the two compounds work the same lever, where a slot goes dark only one of them touches it. read straight from each entry's affinity table; nothing here is invented.
agonist (via 6-MAM and morphine)
agonist
agonist
agonist
agonist
agonist
crosses rapidly
deacetylated by
binds directly
modulates
modulates
strengths are the entries' qualitative ratings (strong / moderate / weak); Ki and EC50 figures appear where an entry records them.