Loading…
for educational and safety purposes
Estradiol and Estriol both come up in the same conversations. Estradiol: Estradiol, often abbreviated E2, is a steroid hormone and the most potent of the naturally occurring estrogens, the principal group of female sex hormones. Estriol: Estriol, abbreviated E3, is a naturally occurring steroid hormone and one of the three principal estrogens, alongside estradiol and estrone.
Estradiol, often abbreviated E2, is a steroid hormone and the most potent of the naturally occurring estrogens, the principal group of female sex hormones. Produced chiefly by the ovaries, it governs the development of female secondary sexual characteristics and the menstrual cycle, and it also plays important roles in bone, brain, and cardiovascular health in both sexes. As a medicine it is used in menopausal hormone therapy, hormonal contraception, feminizing hormone therapy for transgender women, and the treatment of certain hormone deficiencies. It is available in many forms, including tablets, patches, gels, and injections.
Estriol, abbreviated E3, is a naturally occurring steroid hormone and one of the three principal estrogens, alongside estradiol and estrone. It is a comparatively weak estrogen that is barely detectable in non-pregnant women but is produced in large amounts by the placenta during pregnancy. Because it is gentle in its effects, it is used medically, chiefly in Europe, to relieve menopausal vaginal symptoms, and its level in a mother's blood is measured as part of prenatal screening tests.
both fingerprints on one instrument; where the marks line up the two compounds work the same lever, where a slot goes dark only one of them touches it. read straight from each entry's affinity table; nothing here is invented.
agonist
agonist
agonist
agonist
inhibits
activates
modulates
modulates
activates
modulates
thickens and reorients
increases
activates
inhibits
increases or preserves
stimulates
short retention
binds
crosses slowly
raises
improves
strengths are the entries' qualitative ratings (strong / moderate / weak); Ki and EC50 figures appear where an entry records them.
easiest to source: Estradiol is currently listed by more trusted vendors (2), so it's the simpler one to get hold of. for effects and safety, read each full entry; this is educational, not medical advice.