for educational and safety purposes
Every compound in the sci-wiki that affects vascular tone; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.
2 sourced · 1 reference
Midodrine is an orally administered alpha-1 adrenergic receptor agonist used mainly to treat symptomatic orthostatic hypotension, the fall in blood pressure that occurs on standing. It acts as a prodrug, converting in the body to the active compound desglymidodrine, which narrows blood vessels and raises blood pressure. Marketed under brand names such as ProAmatine and Gutron, it was approved for medical use in the United States in 1996 and is now available as a generic.
Ramipril is an angiotensin-converting-enzyme (ACE) inhibitor used to treat high blood pressure and heart failure and to lower cardiovascular risk. It is given as a prodrug that the body converts into its active form, ramiprilat. Widely prescribed, it is available as an inexpensive generic medicine.
Atiprosin is an investigational antihypertensive agent that acts as a selective alpha1-adrenergic receptor antagonist, developed in the 1980s and never marketed.