for educational and safety purposes
Every compound in the sci-wiki that affects urinary flow; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.
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Pygeum is a fat-soluble extract of the bark of Prunus africana (the African cherry, sometimes called the African plum tree), and its whole reputation rests on one job: easing the urinary symptoms of benign prostatic hyperplasia (BPH, the non-cancerous prostate enlargement that makes older men get up at night and struggle to fully empty the bladder). The bark is standardized to a blend of fat-soluble actives; phytosterols like beta-sitosterol, pentacyclic triterpenes, and ferulic acid esters; which together are thought to calm prostate inflammation and soften the hormone and growth-factor signals that drive the gland to swell. It has been used in Europe as a prescription-grade BPH remedy since the 1960s, and it is one of the two herbs (saw palmetto is the other) that men reach for first when they want a plant option before or alongside medication.
Alfuzosin is an alpha-1 adrenergic receptor antagonist, a type of alpha blocker used to relieve the urinary symptoms of an enlarged prostate. Sold under brand names such as Uroxatral and Xatral, it relaxes smooth muscle in the prostate and bladder neck to improve urine flow without shrinking the prostate itself. Taken as a once-daily extended-release tablet, it is a common first-line medical treatment for benign prostatic hyperplasia.