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Follitropin alfa is a manufactured version of human follicle-stimulating hormone (FSH), the hormone that drives the growth of egg-containing follicles in the ovaries. It is made using recombinant DNA technology, in which cells engineered to carry the human FSH gene produce the hormone, and it is given by injection. Best known under the brand name Gonal-f, it is used mainly in fertility treatment to stimulate the ovaries for procedures such as in vitro fertilisation, and it can also treat some forms of infertility in men. Studies find it works about as well as older FSH products purified from urine.
Urofollitropin is a purified preparation of follicle-stimulating hormone (FSH) obtained from the urine of postmenopausal women. Used in fertility medicine, it stimulates the ovaries to develop follicles for ovulation induction and for assisted reproduction such as in vitro fertilisation. It has been sold under brand names including Bravelle, Fostimon and Metrodin, and works much like recombinant FSH [1].