prolactin

Every compound in the sci-wiki that affects prolactin; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

2 sourced · 0 reference

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Dopaminergic

Bromocriptine

Bromocriptine is a dopamine receptor agonist derived from ergot, acting mainly at the dopamine D2 receptor. It is used to treat conditions linked to excess prolactin, such as prolactinomas and related infertility, as well as Parkinson disease, acromegaly, and, in a quick-release form, type 2 diabetes. Discovered by Sandoz in the 1960s, it was approved for medical use in the 1970s.

2 outlets

Dopaminergic

Pramipexole

Pramipexole is a non-ergoline dopamine agonist used mainly to treat Parkinson's disease and restless legs syndrome. It works by directly stimulating dopamine receptors in the brain, with a preference for the D3 subtype, standing in for the dopamine signalling that is lost in Parkinson's disease. First approved in the United States in 1997 and sold under names such as Mirapex, Mirapexin and Sifrol, it is available as immediate-release and extended-release tablets and has also been studied off-label for depression.

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