Nerve health

Every compound in the sci-wiki that affects nerve health; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

3 sourced · 0 reference

←nerve health3/3

Mitochondrial

ALA

Alpha-lipoic acid (ALA), also called lipoic acid or thioctic acid, is a naturally occurring organosulfur compound that serves as an essential cofactor for several mitochondrial enzymes involved in energy metabolism. It is soluble in both water and fat and is widely marketed as a dietary antioxidant supplement, while in some countries a pharmaceutical form is used to treat the symptoms of diabetic neuropathy.

3 outlets

Nootropic

Methylcobalamin

Methylcobalamin, also called mecobalamin, is a naturally occurring form of vitamin B12 in which the cobalt atom carries a methyl group. It is one of the two coenzyme forms of the vitamin that are active in the human body, serving as an essential cofactor for the enzyme methionine synthase. Methylcobalamin is used as a dietary supplement and, in some countries, as a medicine, and it can prevent or correct vitamin B12 deficiency in the same way as other B12 forms.

2 outlets

Blend

Pregabalin + Nortriptyline + Methylcobalamin

Pregabalin with nortriptyline and methylcobalamin is a fixed-dose combination product used mainly for nerve pain, particularly the painful diabetic peripheral neuropathy commonly treated in South Asia, where such combinations are widely marketed. It brings together three ingredients with different roles: pregabalin, a gabapentinoid that calms overactive nerve signalling; nortriptyline, a tricyclic antidepressant long used for neuropathic pain; and methylcobalamin, an active form of vitamin B12 involved in nerve health. It is not sold as a single approved medicine in regions such as the United States or Europe, and the supporting evidence comes largely from studies of its individual components.

1 outlet