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Levodopa + carbidopa is a fixed-dose combination medication used chiefly to treat Parkinson's disease. Levodopa is a precursor that the brain converts into dopamine, the neurotransmitter that is depleted in the disease, while carbidopa prevents levodopa from being broken down before it reaches the brain. Sold under brand names such as Sinemet, the pairing remains the most effective symptomatic treatment for Parkinson's disease.
Ropinirole is a non-ergoline dopamine agonist, a drug that mimics the action of dopamine at its receptors in the brain. It is used mainly to treat Parkinson's disease and moderate to severe restless legs syndrome. Taken by mouth, it is sold under brand names such as Requip.