MAO-B

Every compound in the sci-wiki that affects mao-b; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

0 sourced · 2 reference

←mao-b2/2

Nootropic

Hemantane

Hemantane is a Russian aminoadamantane (a cage-shaped adamantane molecule carrying an amine group, the same chemical family as amantadine) developed at the Zakusov Institute of Pharmacology as an experimental antiparkinsonian and analgesic (pain-relieving) drug. It works through several linked actions at once: it is a low-affinity blocker of the NMDA glutamate receptor, it raises dopamine in the striatum, and it weakly and reversibly inhibits the enzyme MAO-B. It is essentially unknown outside Russian-language research and has no established use in Western medicine.

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Nootropic

p-Fluoro-Deprenyl

p-Fluoro-Deprenyl is a para-fluoro analog of selegiline (deprenyl), a selective inhibitor of monoamine oxidase B (MAO-B, an enzyme that breaks down dopamine and related amines in the brain). It is largely a research compound of interest for the catecholaminergic and neuroprotective effects seen with the selegiline family. The fluorine substitution is mainly explored for tuning metabolism and, in labeled form, for brain imaging of MAO-B.

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