Intraocular pressure

Every compound in the sci-wiki that affects intraocular pressure; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

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Dermatological

Bimatoprost

Bimatoprost is a synthetic prostaglandin analog, specifically a prostamide, used to lower pressure inside the eye. Its main medical role is in treating open-angle glaucoma and ocular hypertension, where it reduces intraocular pressure by increasing the drainage of fluid from the eye [1]. A well-known side effect, longer and darker eyelashes, led to a second approved use as a cosmetic treatment for sparse lashes, marketed as Latisse [3]. It is applied as a once-daily eye drop or, for lashes, as a topical solution, and is sold under brand names including Lumigan.

1 outlet

Cholinergic

Pilocarpine

Pilocarpine is a muscarinic cholinergic agonist, a parasympathomimetic drug originally extracted from the leaves of Pilocarpus (jaborandi) shrubs native to Brazil. In the eye it constricts the pupil and lowers pressure, so it has long been used for glaucoma and, more recently, in low-dose drops for the age-related loss of near vision known as presbyopia. Taken as a tablet it stimulates the salivary glands and is used to relieve dry mouth caused by Sjögren syndrome or radiation therapy.

1 outlet

reference shelf; no outlet carries these yet

Nootropic

Carbachol

A non-selective cholinergic agonist that acetylcholinesterase cannot readily break down; in United States practice it survives as an ophthalmic drug, and in the laboratory as one of the most heavily used tools in cholinergic pharmacology.

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