HIV reverse transcriptase

Every compound in the sci-wiki that affects hiv reverse transcriptase; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

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Emtricitabine + Tenofovir Alafenamide

Emtricitabine and tenofovir alafenamide is a fixed-dose combination of two antiretroviral drugs used to treat and to prevent HIV infection. Both are reverse-transcriptase inhibitors that block the enzyme HIV uses to copy its genetic material. Taken as a once-daily tablet and sold as Descovy, the combination has smaller effects on kidney function and bone density than an older tenofovir formulation.

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Tenofovir Disoproxil Fumarate + Emtricitabine

Tenofovir Disoproxil Fumarate + Emtricitabine is a fixed-dose antiretroviral combination, sold under the brand name Truvada and as many generics, that unites two nucleoside and nucleotide reverse-transcriptase inhibitors active against HIV. Emtricitabine is a cytidine analogue, while tenofovir disoproxil fumarate is an orally absorbed prodrug of the adenine nucleotide analogue tenofovir; together they block the enzyme HIV uses to copy its genetic material. The tablet is taken once daily, both as part of combination treatment for HIV infection and, since 2012, as pre-exposure prophylaxis to lower the risk of acquiring HIV [1][2].

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