Histone acetylation

Every compound in the sci-wiki that affects histone acetylation; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

2 sourced · 1 reference

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Nootropic

Acetyl-L-Carnitine

Acetyl-L-carnitine (ALCAR), also known as levacecarnine, is the acetylated form of the amino-acid derivative L-carnitine. It occurs naturally in the body, where it participates in mitochondrial energy metabolism by helping transport fatty acids for breakdown and by supplying acetyl groups. Sold widely as a dietary supplement and used as a medicine in some countries, it has been studied for depression, nerve pain, and age-related cognitive decline.

3 outlets

Supplement

Magnesium Acetate

Magnesium acetate is the magnesium salt of acetic acid, with the formula Mg(CH3COO)2. It forms white, water-soluble, moisture-absorbing crystals and is used as a food additive, a laboratory buffer, and a source of magnesium. As a dietary ingredient its role is simply to deliver magnesium, an essential mineral, in a soluble form.

1 outlet

reference shelf; no outlet carries these yet

HDAC Inhibitor

Trichostatin A

Trichostatin A, almost always shortened to TSA, is the classic laboratory HDAC inhibitor; it is a natural product first pulled from a Streptomyces bacterium (originally as an antifungal) that turned out to be an extremely potent, reversible blocker of the histone deacetylase family. It is not a medicine and is not used in people; instead it is one of the most heavily used tools in epigenetics research, the reference compound scientists reach for whenever they want to crank up histone acetylation in a dish and watch what happens to gene expression, cell behavior, or cell identity.

reference