herpes simplex virus

Every compound in the sci-wiki that affects herpes simplex virus; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

1 sourced · 1 reference

←herpes simplex virus2/2

Antiviral

Aciclovir

Aciclovir, also spelled acyclovir, is a synthetic guanosine nucleoside analogue used as an antiviral medication against herpesviruses. It is prescribed chiefly for infections caused by herpes simplex virus and varicella zoster virus, including cold sores, genital herpes, chickenpox, and shingles. The selective way it is activated inside virus-infected cells helped earn its developers a share of the 1988 Nobel Prize in Physiology or Medicine, and it remains on the World Health Organization's List of Essential Medicines.

2 outlets

reference shelf; no outlet carries these yet

Topical Formula

Tromantadine

Tromantadine is a topical (skin-applied) antiviral adamantane, sold as Viru-Merz gel, used for herpes simplex infections such as cold sores and genital herpes. Chemically it is an adamantane relative of amantadine, but rather than acting like a flu drug it interferes with the herpes virus at both ends of its life cycle: an early step around viral attachment and entry, and a late step involving the processing of viral glycoproteins (the surface proteins the virus needs to spread and fuse cells). It is applied to lesions rather than taken by mouth.

reference