for educational and safety purposes
Every compound in the sci-wiki that affects gram-negative bacteria; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.
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Ceftriaxone is a broad-spectrum third-generation cephalosporin antibiotic given by injection to treat many serious bacterial infections [1][2]. It stops bacteria from building their cell walls, and an unusually long half-life allows it to be given just once a day [1][2]. It is used for conditions such as bacterial meningitis, pneumonia, gonorrhea, and bloodstream and bone infections, and it is a first-line treatment for gonorrhea [2][3]. Developed by Roche and approved for medical use in 1982 under the brand name Rocephin, ceftriaxone appears on the World Health Organization Model List of Essential Medicines [1].
Levofloxacin is a broad-spectrum antibiotic in the fluoroquinolone class, used to treat bacterial infections such as pneumonia, sinusitis, and urinary tract infections. Chemically it is the more active mirror-image half of an older drug, ofloxacin. It is sold under brand names including Levaquin and, because of serious safety concerns, is now generally reserved for infections where other options are unsuitable.