Estrogen receptor

Every compound in the sci-wiki that affects estrogen receptor; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

1 sourced · 1 reference

←estrogen receptor2/2

Hormone

Fulvestrant

Fulvestrant is an anticancer medicine of the selective estrogen receptor degrader (SERD) class, used to treat hormone receptor-positive breast cancer. Unlike drugs that merely block the estrogen receptor, it binds the receptor and triggers its destruction, shutting down estrogen signalling in tumour cells. Given as a monthly intramuscular injection and sold under the brand name Faslodex, it is used mainly in postmenopausal women with advanced or metastatic disease, often alongside targeted drugs called CDK4/6 inhibitors. It was the first drug of its kind to be approved, reaching the market in 2002.

1 outlet

reference shelf; no outlet carries these yet

SERM

Acefluranol

Acefluranol is a nonsteroidal antiestrogen (a stilbene-derivative selective estrogen receptor modulator with mixed agonist/antagonist activity) that was investigated but never marketed.

reference