for educational and safety purposes
Every compound in the sci-wiki that affects dopamine d2/d3 receptors; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.
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Pramipexole is a non-ergoline dopamine agonist used mainly to treat Parkinson's disease and restless legs syndrome. It works by directly stimulating dopamine receptors in the brain, with a preference for the D3 subtype, standing in for the dopamine signalling that is lost in Parkinson's disease. First approved in the United States in 1997 and sold under names such as Mirapex, Mirapexin and Sifrol, it is available as immediate-release and extended-release tablets and has also been studied off-label for depression.
Ropinirole is a non-ergoline dopamine agonist, a drug that mimics the action of dopamine at its receptors in the brain. It is used mainly to treat Parkinson's disease and moderate to severe restless legs syndrome. Taken by mouth, it is sold under brand names such as Requip.