Collagen synthesis

Every compound in the sci-wiki that affects collagen synthesis; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

2 sourced · 1 reference

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Peptide

Matrixyl

Matrixyl is a trade name for a family of synthetic cosmetic peptides used in anti-aging skincare, the original being palmitoyl pentapeptide-4 (also written pal-KTTKS), a short chain of amino acids attached to a fatty acid. These peptides are designed as matrikines, signal fragments that mimic pieces of broken-down collagen and prompt skin cells to make new collagen and other matrix proteins [1][2]. Marketed as a topical ingredient, palmitoyl pentapeptide has been reported in a controlled study to reduce the appearance of fine lines and wrinkles [1].

1 outlet

Respiratory

Pirfenidone

Pirfenidone is an orally administered antifibrotic and anti-inflammatory drug used to treat idiopathic pulmonary fibrosis, a progressive scarring disease of the lungs. Chemically it is a small pyridinone molecule (5-methyl-1-phenylpyridin-2-one) that slows the loss of lung function by dampening the growth factors and collagen production that drive fibrosis. First approved in Japan in 2008 and later cleared across Europe, North America and elsewhere, it is sold under brand names such as Esbriet and Pirespa.

1 outlet

reference shelf; no outlet carries these yet

Supplement

Calcium L-Threonate

Calcium L-threonate is the calcium salt of L-threonic acid, a metabolite of vitamin C, marketed as a highly absorbable mineral supplement for bone and connective-tissue health [1]. In a human pharmacokinetic study, orally administered L-threonate was absorbed rapidly, was well tolerated across single and repeated doses, and showed enhanced absorption when taken with food [1]. It should not be confused with magnesium L-threonate; calcium L-threonate delivers elemental calcium and its threonate carrier for bone and collagen support, without the blood-brain-barrier and cognitive claims attached to the magnesium form [1].

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