Calcium handling

Every compound in the sci-wiki that affects calcium handling; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

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Nootropic

Apoaequorin

Apoaequorin is the protein component of aequorin, a calcium-sensitive, light-emitting protein originally isolated from the jellyfish Aequorea victoria. In the laboratory it is widely used as a tool for detecting calcium inside cells. It is also the active ingredient in the marketed memory supplement Prevagen, a use for which independent reviewers have found the supporting evidence weak, and which drew a false-advertising action from United States regulators.

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Cardiovascular

S107

S107, also called ARM036, is a member of the Rycal class of small molecules that stabilize ryanodine receptors (RyR), the calcium release channels of the sarcoplasmic and endoplasmic reticulum. By preserving the binding of the stabilizing subunit calstabin to leaky RyR channels, S107 reduces pathological intracellular calcium leak implicated in heart failure and arrhythmia [1][2], muscle fatigue and reduced exercise capacity [3], muscular dystrophy [4], and stress-related cognitive dysfunction [5].

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