ATP synthesis

Every compound in the sci-wiki that affects atp synthesis; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

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Mitochondrial

TND-1128

TND-1128 (TND1128) is a lipophilic 5-deazaflavin derivative developed in Japan as a mitochondrial activator with efficient self-redox ability. In preclinical work it enhances mitochondrial membrane potential and on-demand ATP synthesis in mouse brain tissue, and it is being explored as a neuro-energetic agent for conditions linked to mitochondrial dysfunction, including neurodegeneration and depression [1][2].

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Mitochondrial

Deazaflavin

Deazaflavin (5-deazaflavin) is a redox-active analog of the flavin cofactor in which the nitrogen at position 5 of the isoalloxazine ring is replaced by carbon. This substitution shifts its chemistry toward two-electron hydride transfer, giving it distinctive self-redox and cofactor-like behaviour that is exploited in nature (for example as coenzyme F420 in certain microbes) and, in medicinal chemistry, as the parent scaffold for mitochondria-targeted derivatives such as TND1128 [1].

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