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compare compounds

class, effects, and the receptor fingerprint, side by side; add up to four, then source the whole stack

Popular head-to-heads →

reading the marksactivatesblocks / inhibitsmodulates

70AD

Mirtazapine

AntidepressantNaSSAAlpha-2 AntagonistSedative

effects: Serotonin, Norepinephrine, histamine (H1), Appetite, Sleep
suppliers: 2 outlets

Receptor fingerprint

Alpha-2 adrenergic autoreceptorantagonist

strongKi = 20 nM

Histamine H1 receptorantagonist

strongKi = 1.6 nM

Serotonin 5-HT2A receptorblocks

moderateKi = 2 nM

Serotonin 5-HT2C receptorblocks

moderateKi = 5.5 nM

Serotonin 5-HT3 receptorblocks

strong

70AD

Esmirtazapine

AntidepressantSleep SupportDeep Cut

effects: Histamine, Serotonin, Norepinephrine
suppliers: reference only

Receptor fingerprint

Histamine H1Antagonist

strong

Alpha-2 adrenergic autoreceptorAntagonist

moderate

5-HT2A/2CAntagonist

moderate

5-HT3Antagonist

moderate

Add compound

no matches for “”

stack compatibility

OverallNo data

checking Mirtazapine and Esmirtazapine: no notable interaction flagged; they read as broadly independent.

Mirtazapine + Esmirtazapine
No data
no notable interaction flagged; these look broadly independent.

Check interactions →

General educational info, not medical advice.