for educational and safety purposes

compare compounds

class, effects, and the receptor fingerprint, side by side; add up to four, then source the whole stack

Popular head-to-heads →

reading the marksactivatesblocks / inhibitsmodulates

14NP

Memantine

Neuroprotection

effects: Glutamate, Dopamine, Serotonin, Acetylcholine
suppliers: 2 outlets

Receptor fingerprint

NMDA receptor (open channel; GluN2C/GluN2D-preferring)uncompetitive, voltage-dependent open-channel antagonist

strongKi ~0.5-1 uM; GluN2C/2D IC50 ~0.2-0.6 uM

Dopamine D2 receptor (high-affinity D2High state)agonist

strongKi ~137 nM (D2High); ~917 nM (D2 striatal)

5-HT3 serotonin receptornon-competitive antagonist

strongIC50 ~0.37 uM

Alpha-9/alpha-10 nicotinic ACh receptorantagonist

moderateIC50 ~0.3-1 uM

Alpha-7 nicotinic ACh receptornon-competitive open-channel antagonist

moderateIC50 ~5 uM

Alpha-4/beta-2 nicotinic ACh receptorantagonist

weakIC50 ~1-7 uM

Alpha-3/beta-4 (ganglionic) nicotinic ACh receptorantagonist

weakIC50 ~1.5-6 uM

Sigma-1 receptoragonist

weakKi ~2.6 uM

Acetylcholinesterasenegligible inhibitor

weak>10 uM

Organic cation transporters (OCT1, OCT2, MATE1)substrate and weak inhibitor

weakOCT1 IC50 ~27 uM

14NP

Homotaurine

NeuroprotectionSupplementProdrugDeep Cut

effects: Amyloid-beta aggregation, Amyloid-beta oligomers, gaba-a receptor, Memory, Neuroprotection
suppliers: reference only

Receptor fingerprint

Amyloid-beta 42 monomersmulti-ligand enveloping stabilization

moderate

Amyloid-beta oligomer and fibril formationinhibits aggregation

moderate

Hippocampal atrophyslows volume loss (imaging)

moderate

Plasma p-tau181 (biomarker)lowers (ALZ-801, APOE4 carriers)

moderate

GABA-A receptoragonist / modulator (taurine-like)

weakIC50 ~300 nM

Add compound

no matches for “”

stack compatibility

OverallNo data

checking Memantine and Homotaurine: no notable interaction flagged; they read as broadly independent.

Memantine + Homotaurine
No data
no notable interaction flagged; these look broadly independent.

Check interactions →

General educational info, not medical advice.