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for educational and safety purposes
class, effects, and the receptor fingerprint, side by side; add up to four, then source the whole stack
Popular head-to-heads →Electron transport chainShuttles electrons for ATP production
Lipid membranesPrevents lipid peroxidation
Cardiac muscleSupports myocardial energetics
Mitochondrial Complex IIIDonates electrons in its reduced form, bypassing impaired Complex I
NQO1 (quinone reductase)Reduced by NQO1 to its active hydroquinone
Lipid peroxidationScavenges free radicals and protects membranes
AMPA receptor currents (indirect, via ATP)extra ATP prolongs excitatory AMPA currents
NQO1 (NAD(P)H quinone oxidoreductase 1)Substrate; reduced by cytosolic NQO1 to the hydroquinone idebenol, which is the only form that carries electrons or scavenges cleanly
Mitochondrial Complex IINHIBITS it in the oxidized state, forming an unstable semiquinone
CYP3A4Mild inhibitor; a dedicated midazolam interaction study was run (NCT02887443)
P-glycoprotein (ABCB1)May inhibit it, raising exposure to substrates such as dabigatran and digoxin
checking CoQ10 and Idebenone: no adverse interactions were flagged (1 compatible pair); the pairs read as compatible at the class level.
noted as a compatible pairing in Idebenone's own profile; no adverse interaction flagged.
General educational info, not medical advice.
The vendors that carry the most of your 2 picks; fewer vendors, fewer codes, less shipping.
Carries CoQ10
Carries CoQ10
codeRDR1015Carries CoQ10
codeSeanNo single vendor carries the whole stack — the top pick covers 1 of 2 sourceable picks; grab the rest from the next vendor.