Tumor cell proliferation

Every compound in the sci-wiki that affects tumor cell proliferation; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

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Antineoplastic

Acivicin

Acivicin is a natural glutamine antagonist, originally isolated from Streptomyces sviceus, that was investigated as an antineoplastic (anticancer) agent for its ability to irreversibly block glutamine-dependent enzymes.

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Supplement

JBSNF-000088

JBSNF-000088 is a small-molecule inhibitor of nicotinamide N-methyltransferase (NNMT), a cytosolic enzyme that methylates nicotinamide using S-adenosylmethionine [1]. Originally reported as a nicotinamide analogue that reduces 1-methylnicotinamide levels and improves insulin sensitivity and body weight in obese and diabetic mice, it has since become a widely used NNMT-inhibitor tool compound in cancer and metabolic research [1]. Notably, it is not a TAAR1 agonist or monoamine modulator; its target is NNMT.

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