spinal cord

Every compound in the sci-wiki that affects spinal cord; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.

1 sourced · 1 reference

←spinal cord2/2

Amino Acid

L-Threonine

L-Threonine is one of the nine essential amino acids; the body can't make it, so it has to come from diet. It's a building block for protein and a source of glycine and serine, and the gut uses a large share of dietary threonine to build mucin, the protective mucus layer that lines the intestine. It's sold as a supplement, though for most people a normal protein intake already covers the requirement.

1 outlet

reference shelf; no outlet carries these yet

Anesthetic

Alphadolone

Alphadolone (alfadolone; clinically alphadolone acetate) is a synthetic neuroactive pregnane steroid (a laboratory-made steroid that acts on the nervous system) which potentiates the GABA-A receptor, the brain's principal fast inhibitory chloride channel, to produce sedation and anaesthesia. It is best known as the minor component of the intravenous anaesthetic Althesin (for humans) and Saffan (for animals), where it was combined with the more potent alfaxalone in a 3:1 ratio, added chiefly to improve the poor water solubility of alfaxalone while still contributing roughly half of that agent's anaesthetic potency in its own right. Both preparations were dissolved in the surfactant Cremophor EL, whose tendency to trigger histamine release and anaphylactoid reactions led to the withdrawal of Althesin from human use in 1984. Alphadolone later attracted independent research interest because, unlike alfaxalone, it produces spinally mediated analgesia without sedation when given by mouth or intraperitoneally, an effect thought to depend on an analgesic metabolite formed in the liver.

reference