for educational and safety purposes
Every compound in the sci-wiki that affects nitric oxide synthase; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.
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MNT (PMP) is a combination injectable and pre-workout formula that pairs nitric oxide precursors with a focused cognitive stack in a single shot. Arginine, citrulline, and the arginase inhibitor norvaline drive vasodilation and blood flow for a stronger pump, while citicoline, N-acetyl-L-tyrosine, and trimethylglycine sharpen focus and support drive under load. It is engineered as a two-in-one performance blend that delivers physical pump and mental clarity together.
Agmatine is a small biogenic amine produced in the body from the amino acid arginine by the enzyme arginine decarboxylase, and it also occurs in fermented foods. Rather than acting on a single dedicated receptor, it is a neuromodulator that engages several systems at once: it is an endogenous ligand at imidazoline receptors, blocks the open pore of the NMDA glutamate receptor, and inhibits neuronal nitric oxide synthase, in part by acting as a suicide substrate that irreversibly destroys the enzyme's heme. It is studied for possible roles in pain, mood, opioid tolerance, and neuroprotection, and is sold as a dietary supplement in the form of agmatine sulfate.