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Every compound in the sci-wiki that affects nasal mucosa; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.
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Azelastine + Fluticasone Propionate is a combination nasal spray, sold under the brand name Dymista, that delivers an antihistamine (azelastine) and a corticosteroid (fluticasone propionate) together from a single device. It is used to treat allergic rhinitis, the nasal and eye symptoms of hay fever and other allergies. By pairing two drugs with different actions it relieves symptoms such as congestion, runny nose, sneezing, and itching more completely and more quickly than either component alone.
Fluticasone furoate combined with azelastine is a combination nasal spray used to treat allergic rhinitis, marketed under the brand name Ryaltris. It pairs two different kinds of allergy medicine in a single device: azelastine, an antihistamine, and fluticasone furoate, a corticosteroid. The aim is to tackle the sneezing, itching, runny nose, and congestion of hay fever from more than one direction at once. Both ingredients act locally in the nose rather than throughout the body.
Nitric oxide (NO) is a colorless gas and free radical that serves as one of the body's most important signaling molecules. Produced naturally in blood vessels, nerves, and immune cells, it relaxes vascular smooth muscle to widen blood vessels and increase blood flow, and it also participates in neurotransmission and host defense. Its identification as the endothelium-derived relaxing factor earned Robert Furchgott, Louis Ignarro, and Ferid Murad the 1998 Nobel Prize in Physiology or Medicine. In medicine, nitric oxide is delivered as an inhaled gas to relax the lung's blood vessels in newborns with pulmonary hypertension.