for educational and safety purposes
Every compound in the sci-wiki that affects gut motility; the ones you can source are floated to the front, then the reference-only entries. Tap any for the full entry, mechanism, and outlets.
0 sourced · 2 reference
McN-A-343 is a quaternary muscarinic agonist that served for decades as the standard tool for identifying M1-mediated responses, and which is now understood to owe that apparent selectivity to uneven efficacy and to a second, allosteric binding site rather than to selective binding.
The fungal alkaloid that muscarinic receptors are named after; it has no therapeutic use and matters today as the toxin behind Inocybe and Clitocybe mushroom poisoning.